| # | Platform | Semaglutide | Tirzepatide | Why it ranks |
|---|---|---|---|---|
| 1 | Wellorithm | From $88/month ongoing | From $249 first month | Lowest ongoing price we trust + 90-day guarantee |
| 2 | Enhance MD | $49 first month | $99 first month | Most aggressive intro pricing |
| 3 | Hume Care Plus | Aggressive launch pricing | Aggressive launch pricing | Full protocol included — best value per dollar |
| 4 | Gala | Competitive flat pricing | Competitive flat pricing | Same price at every dose, no surprises |
| 5 | ShedRx | Transparent pricing | Transparent pricing | No hidden charges at checkout |
1. Wellorithm — best long-term price
Wellorithm remains our top recommendation, and here's why: compounded semaglutide starts at $88 per month — the lowest ongoing price we found on a platform we actually trust. Care, coaching and clinical supervision are included, plus a 90-day guarantee. Other platforms win on the first month; if you're thinking long-term, Wellorithm is still the benchmark.
Check current Wellorithm pricing · Read our full review
2. Enhance MD — most aggressive first-month deal
Enhance MD's recent price drop is the kind of intro offer you rarely see from a clinically serious platform: semaglutide at $49 for your first month and tirzepatide at $99. Real medical supervision, a personalized protocol, and a team that actually follows up. If you want the lowest possible cost to try GLP-1 therapy, this is it.
Check current Enhance MD pricing
3. Hume Care Plus — most value per dollar
Hume Care Plus isn't always the lowest sticker price, but it's the most program for your money right now: the launch pricing includes the full protocol — muscle-preservation supplements, weekly body scans and a 24/7 in-app doctor — at rates we don't expect to survive once they've grabbed market share. Our full review explains why it's our overall #1.
Check current Hume Care Plus pricing · Read our full review
4. Gala — flat pricing, zero surprises
Gala's pitch is simple: the price you see is the price you pay, at every dose. No jump when you move to the maintenance dose, no surprise fees at checkout, and a concierge-style service with real humans in support. If bait pricing is what you're afraid of, Gala is the antidote.
5. ShedRx — transparent compounded pricing
ShedRx is one of the platforms our research flagged as genuinely trustworthy on price: no surprise fees, no hidden charges at checkout, and medical support included from prescription to delivery. A straightforward, honest option for compounded GLP-1 therapy.
Before you pay cash: check Medicare
For cash payers, brand-name options like Wegovy and Zepbound still run around $350/month for starting doses. The compounded telehealth platforms above can drop that number dramatically — and if you're uninsured, our GLP-1 without insurance guide covers manufacturer savings cards and assistance programs that can cut costs even further.
How this tracker works
Each week we reach out directly to the platforms we consider legitimate and compare their offers. Some don't respond — in that case we verify their websites directly. Either way, the goal is a clear, accurate picture of the deals running over the next 7 days. Stay sharp: there are shady players in this market counting on people not knowing better. If a price seems impossibly low and there's no doctor involved, walk away.
Prices verified during the week shown above and subject to change. Medical disclaimer: GLP-1 therapy is prescription treatment — always consult a licensed healthcare provider.