| # | Platform | Semaglutide | Tirzepatide | Why it ranks |
|---|---|---|---|---|
| 1 | AbundRX | $99/month, medication included | $149/month, medication included | Cheapest all-in price: the medication is inside the number |
| 2 | Wellorithm | From $88/month ongoing | From $249 first month | Lowest ongoing price we trust + 90-day guarantee |
| 3 | Enhance MD | $49 first month | $99 first month | Most aggressive intro pricing |
| 4 | Hume Care Plus | Aggressive launch pricing | Aggressive launch pricing | Full protocol included, best value per dollar |
| 5 | DocSearch | $149/month, flat at every dose | $179/month, flat at every dose | Same price through the whole titration, $0 until prescribed |
| 6 | TrimRx | From $168/month all-in | From $168/month all-in | Same price at every dose, oral option available |
| 7 | Gala | Competitive flat pricing | Competitive flat pricing | Same price at every dose, no surprises |
| 8 | ShedRx | Transparent pricing | Transparent pricing | No hidden charges at checkout |
| 9 | Aspen Health | $199 first month, then $299 · $179/mo prepaid year | $299 first month, then $399 · $289/mo prepaid year | Flat at every dose, but the cheap tier needs a year up front |
🥇 AbundRX: the cheapest all-in price
AbundRX is the cheapest all-in program we have reviewed, and the reason is what sits inside the number. Semaglutide-based care starts at $99 a month and tirzepatide at $149, with the provider review, the care planning, the follow-up and the medication fulfillment included rather than arriving as a separate pharmacy bill. That $149 tirzepatide rate is the one to stare at: it is what the cheapest semaglutide programs charge, against a US cash-pay average of about $347 a month. It is LegitScript certified, names its providers and publishes a real address. The caveats are that the platform is new, so there is no long track record yet, and the $99 rate is promotional and tied to the official link.
Check the $99 access price · Read our full review
🥈 Wellorithm: best long-term price
Wellorithm remains our top recommendation, and here's why: compounded semaglutide starts at $88 per month, the lowest ongoing price we found on a platform we actually trust. Care, coaching and clinical supervision are included, plus a 90-day guarantee. Other platforms win on the first month; if you're thinking long-term, Wellorithm is still the benchmark.
Check current Wellorithm pricing · Read our full review
🥉 Enhance MD: most aggressive first-month deal
Enhance MD's recent price drop is the kind of intro offer you rarely see from a clinically serious platform: semaglutide at $49 for your first month and tirzepatide at $99. Real medical supervision, a personalized protocol, and a team that actually follows up. If you want the lowest possible cost to try GLP-1 therapy, this is it.
Check current Enhance MD pricing
4️⃣ Hume Care Plus: most value per dollar
Hume Care Plus isn't always the lowest sticker price, but it's the most program for your money right now: the launch pricing includes the full protocol (muscle-preservation supplements, weekly body scans and a 24/7 in-app doctor) at rates we don't expect to survive once they've grabbed market share. Our full review explains why it's our overall #1.
Hume also runs a separate oral protocol, priced from $199 a month, for anyone whose objection was never the price but the needle. Same weekly body scans and muscle-protection supplements, nothing to inject, and a refund promise attached to losing 10% in six months. We cover it in the HumeCare+ Oral review.
Check current Hume Care Plus pricing · Check the oral protocol · Read our full review
5️⃣ DocSearch: the price that stops climbing
DocSearch starts at $149 a month for compounded semaglutide and $179 for tirzepatide, and the detail that earns it a place here is that the figure is held flat through the entire titration. Same price at the starter dose, same price at the dose that is actually doing the work. That is the month-four bill shock that ends more GLP-1 programs than side effects do, removed. The consultation, the prescription, discreet shipping, syringes and supplies and messaging the care team are inside the plan price, with no membership and no consult fee added afterwards. Your card is authorized at $0 and only charged once a licensed US physician issues a prescription, and you are refunded in full if you are not prescribed. LegitScript certified on both the telehealth and the pharmacy side. The catch to know: the three-month plan at $567 works out to $189 a month, above the monthly rate rather than below it.
Check the $149 flat price · Read our full review
6️⃣ TrimRx: the price that doesn't move
TrimRx starts at $168 per month, and the number that matters is that it's flat: the same figure at your starting dose and at the maintenance dose, so titrating up costs you nothing extra. The medical visit, the prescription, 24/7 support and shipping are inside that price rather than billed on top, and it's one of the few platforms here with a needle-free oral GLP-1+GIP option. Cheaper first-month deals exist above, but they're first-month deals. There's currently $200 off plus free shipping.
Check current TrimRx pricing · Read our full review
7️⃣ Gala: flat pricing, zero surprises
Gala's pitch is simple: the price you see is the price you pay, at every dose. No jump when you move to the maintenance dose, no surprise fees at checkout, and a concierge-style service with real humans in support. If bait pricing is what you're afraid of, Gala is the antidote.
8️⃣ ShedRx: transparent compounded pricing
ShedRx is one of the platforms our research flagged as genuinely trustworthy on price: no surprise fees, no hidden charges at checkout, and medical support included from prescription to delivery. A straightforward, honest option for compounded GLP-1 therapy.
Before you pay cash: check Medicare
For cash payers, brand-name options like Wegovy and Zepbound still run around $350/month for starting doses. The compounded telehealth platforms above can drop that number dramatically, and if you're uninsured, our GLP-1 without insurance guide covers manufacturer savings cards and assistance programs that can cut costs even further.
How this tracker works
Each week we reach out directly to the platforms we consider legitimate and compare their offers. Some don't respond, and in that case we verify their websites directly. Either way, the goal is a clear, accurate picture of the deals running over the next 7 days. Stay sharp: there are shady players in this market counting on people not knowing better. If a price seems impossibly low and there's no doctor involved, walk away.
Prices verified during the week shown above and subject to change. Medical disclaimer: GLP-1 therapy is prescription treatment, so always consult a licensed healthcare provider.